Why You Should Consider Cryotherapy

If your periods are extremely painful or unusually heavy, meaning they last longer than a week or you change your tampon or pad every hour, you might have a condition called “heavy menstrual bleeding”, also referred to as “menorrhagia”.1

Heavy bleeding is very common; in fact, it is one of the most frequently reported women’s health problems.1 It’s estimated that over 10 million women in the U.S. suffer from heavy periods and experience a reduced quality of life due to excessive blood loss and debilitating pain.1

Finding the right treatment

If you suspect you may have heavy periods, the first step is to make an appointment with your OBGYN. During this visit, you will discuss each available treatment option and choose the one that’s best for you, your health, and your future plans for pregnancy.

The first general treatment category is hormone therapy, such as birth control medication (“the pill”), IUDs, or injectables. If hormone therapy doesn’t work, your gynecologist may recommend a procedure to help reduce the bleeding and pain. The most common procedures used to treat heavy periods are endometrial ablation and hysterectomy.

While a hysterectomy removes the source of the problem — your uterus — it involves an invasive procedure with long recovery times and a higher risk of complications versus other treatment options. For patients wishing to avoid major surgery, endometrial ablation offers a less invasive alternative that effectively provides relief from heavy periods.

Endometrial ablation employs a variety of techniques using either heat- or cold-based technology to destroy the tissue on the inner uterine lining (the endometrium). This is the tissue that sheds blood each month during your period. Removing endometrial tissue can help your periods become lighter and less painful.

Why cryotherapy may be the answer

Endometrial cryoablation uses cooling technology (cryotherapy) to destroy endometrial tissue. Cryotherapy is advantageous because the extreme cold used in the treatment provides a natural pain-relieving, or numbing, effect during treatment, eliminating the need for general anesthesia or IV sedation. This enables your doctor to perform these ablations in their office, where you may feel more comfortable than in a hospital operating room. 

How the Cerene® Cryotherapy Device can help 

The Cerene Cryotherapy Device is an FDA-approved endometrial cryoablation technology that uses nitrous oxide to freeze the endometrial tissue responsible for heavy periods. Cerene was designed to prioritize the patient experience by naturally minimizing pain during and after the treatment, allowing for an in-office treatment experience with no anesthesia. A clinical study has shown an average median pain score during the treatment is a 2 out of 10, with a median score of 0 out of 10 the day after treatment.

In addition to a well-tolerated and convenient treatment, Cerene is clinically proven to deliver lasting relief from heavy periods. One year after treatment with Cerene, 90% of patients were satisfied with their results, and 95% said they would recommend Cerene to their family and friends.†† 

If you’re ready to get your life back from heavy periods, talk to your doctor about Cerene to see if cryotherapy can help reduce your bleeding and relieve your pain.

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† Patient-reported data are 1 year after treatment with durable results at 3 years

†† Patient-reported data include definitely and consider recommending Cerene and are 1 year after treatment with durable results at 3 years

Key Takeaways: 

  • Over 10 million women in the U.S. suffer from heavy periods and experience a reduced quality of life due to extensive blood loss and debilitating pain.1
  • Cryotherapy uses cooling technology to effectively destroy uterine tissue while providing a natural pain-relieving effect during the treatment.
  • Cerene is clinically proven to provide lasting relief from heavy periods with an in-office treatment that requires no anesthesia.

Important Safety Information

Cerene® Cryotherapy Device is indicated to ablate the endometrial lining of the uterus in premenopausal women with heavy menstrual bleeding due to benign causes for whom childbearing is complete. Pregnancy following the Cerene procedure can be dangerous; therefore, contraception must be used until menopause. The Cerene procedure is not for those who have or suspect uterine cancer; have an active genital, urinary or pelvic infection; or an IUD. There are risks and considerations associated with the use of the Cerene Cryotherapy Device. Temporary side effects may include uterine cramping, vaginal infection, and lightheadedness. For detailed benefit and risk information, consult the Cerene Instructions for Use (IFU) or your healthcare professional. Learn more >


  1. Heavy Menstrual Bleeding. (n.d.), Centers for Disease Control and Prevention, Retrieved January 17, 2023, from 
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