How Cerene®

Cerene Cryotherapy

The Cerene Cryotherapy Device is FDA approved for endometrial cryoablation and treats heavy menstrual bleeding while minimizing pain. The treatment does not require general anesthesia and is aided by the natural numbing effects from the cryotherapy process. Cerene is for premenopausal women with heavy menstrual bleeding due to benign causes for whom child bearing is complete.

2.5 minute cryoablation treatment time
Gradual uterine pressurization and distention for patient comfort
Conveniently designed to fit into your practice routine
See Cerene in Action
Cerene Cryotherapy Device
  • Self-contained single-use system does not require capital equipment, so any room becomes a procedure room
  • Simple one-button device design, step-by-step guidance on the LCD screen, and a slim 6mm probe with flexible distal end that conforms to the uterine cavity
  • Radiopaque, thermally-insulating sheath facilitates accurate placement and visualization on ultrasound
  • Precise and automatically controlled treatment parameters
  • Multi-tiered safety features

Important Safety Information

Cerene® Cryotherapy Device is indicated to ablate the endometrial lining of the uterus in premenopausal women with heavy menstrual bleeding due to benign causes for whom childbearing is complete. Pregnancy following the Cerene procedure can be dangerous; therefore, contraception must be used until menopause. The Cerene procedure is not for those who have or suspect uterine cancer; have an active genital, urinary or pelvic infection; or an IUD. There are risks and considerations associated with the use of the Cerene Cryotherapy Device. Temporary side effects may include uterine cramping, vaginal infection, and lightheadedness. For detailed benefit and risk information, consult the Cerene Instructions for Use (IFU) or your healthcare professional. CAUTION: Federal (USA) law restricts this device to sale by or on the order of a physician trained in the use of the Cerene Cryotherapy Device. Learn More