The Cerene®
Treatment
What is Cerene?

Cerene is a treatment designed to significantly reduce heavy period bleeding and cramping so you can get you back to enjoying life. Performed in the comfort and familiarity of your doctor’s office, Cerene naturally provides relief by using cooling technology to treat your heavy periods.

Period
Relief
Significantly reduces heavy bleeding and cramping with most returning to daily activities within 24 hours
Convenient
Treatment
A treatment that can be performed comfortably in your doctor’s office
High
Satisfaction
9 out of 10 women had little to no limitations in their activities after Cerene†
Real Patient Results
were satisfied
with Cerene†
would recommend Cerene to family and friends††
had normal, light, or no periods after Cerene†
had a reduction in cramping†††

† Patient-reported data are 1 year after treatment with durable results at 3 years
†† Patient-reported data include definitely and consider recommending Cerene and are 1 year after treatment with durable results at 3 years
††† Improvement reported one year after treatment for patients reporting severe/very severe cramping

How Does Cerene Work?

Cerene is an endometrial ablation treatment that uses cooling technology (cryotherapy) to remove the lining of the uterus (endometrium), which is often the cause of heavy bleeding and discomfort. Cryotherapy provides a natural pain relieving effect during the treatment, without the need for general anesthesia. 92% of patients said their pain level was at or below the acceptable median pain score during treatment.

Step 1
Cerene Device is inserted

The Cerene Device is gently inserted into the uterus, and safety checks are completed.

Step 2
Uterine cavity is treated

Cryotherapy is delivered for 2.5 minutes to treat the endometrium, while providing a natural, pain-relieving effect.

Step 3
Cerene Device is removed

At the end of the treatment, the Cerene Device is carefully removed.

See Questions to Ask Your Doctor
Resources
Patient Stories
See what patients are saying about Cerene
Patient Stories
Frequently Asked Questions
Get answers to the most commonly asked questions.
Frequently Ask Questions
What Are Heavy Periods?
Find out if you might be suffering with heavy periods.
What are Heavy Periods?
Find A Doctor
Contact a gynecologist to see if Cerene is right for you.
Find A Doctor

Important Safety Information

Cerene® Cryotherapy Device is indicated to ablate the endometrial lining of the uterus in premenopausal women with heavy menstrual bleeding due to benign causes for whom childbearing is complete. Pregnancy following the Cerene procedure can be dangerous; therefore, contraception must be used until menopause. The Cerene procedure is not for those who have or suspect uterine cancer; have an active genital, urinary or pelvic infection; or an IUD. There are risks and considerations associated with the use of the Cerene Cryotherapy Device. Temporary side effects may include uterine cramping, vaginal infection, and lightheadedness. For detailed benefit and risk information, consult the Cerene Instructions for Use (IFU) or your healthcare professional. CAUTION: Federal (USA) law restricts this device to sale by or on the order of a physician trained in the use of the Cerene Cryotherapy Device. Learn More